Engineering Lactobacillus rhamnosus GG and GR-1 to express HIV-inhibiting griffithsin
نویسندگان
چکیده
منابع مشابه
Bile Resistance in Lactobacillus rhamnosus GG: Stability and Mechanisms
Lactobacillus rhamnosus GG is a lactic acid bacterium that is widely used as probiotic products in the dairy industry. To gain insights into the genome stability of the L. rhamnosus GG in the human gastrointestinal tract and the possible adaption mechanism under different stresses, we first examined the genotype and phenotype of the L. rhamnosus GG grown over 1000 generations under various stre...
متن کاملTowards a better understanding of Lactobacillus rhamnosus GG - host interactions
Lactobacillus rhamnosus GG (LGG) is one of the most widely used probiotic strains. Various health effects are well documented including the prevention and treatment of gastro-intestinal infections and diarrhea, and stimulation of immune responses that promote vaccination or even prevent certain allergic symptoms. However, not all intervention studies could show a clinical benefit and even for t...
متن کاملEffects of Lactobacillus rhamnosus GG on saliva-derived microcosms.
OBJECTIVE The probiotic strain Lactobacillus rhamnosus GG (LGG) is shown to hamper the presence of mutans streptococci in saliva and may have positive effects on oral health. We investigated the effects of LGG on the cariogenic potential and microbial composition of saliva-derived microcosms. DESIGN Single and dual species biofilms of LGG and Streptococcus mutans, and saliva-derived microcosm...
متن کاملStability of Lactobacillus rhamnosus GG in prebiotic edible films
The concept of prebiotic edible films as effective vehicles for encapsulating probiotic living cells is presented. Four soluble fibres (inulin, polydextrose, glucose-oligosaccharides and wheat dextrin) were selected as prebiotic co-components of gelatine based matrices plasticised with glycerol and used for the immobilisation of Lactobacillus rhamnosus GG. The addition of prebiotics was associa...
متن کاملLactobacillus rhamnosus GG Protects Cells from Clostridium difficile Toxins
Aims: To determine the anti-cytotoxic effects of Lactobacillus rhamnosus GG (LGG) against extracellular and intracellular Clostridium difficile toxins. Study Design: Co-culture system. Place and Duration of Study: Division of Infectious Diseases, Department of Medicine, School of Medicine and Public Health and Department of Pathobiological Sciences, School of Veterinary Medicine, Madison, Wisco...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Antimicrobial Agents
سال: 2018
ISSN: 0924-8579
DOI: 10.1016/j.ijantimicag.2018.07.013